Across 62 countries, people receiving PrEP at least once declined by 38% between 2024 and 2025, in part due to U.S. aid cuts.
Date: 6/26
Region: Global
Country: Global
Topic: Health
Policy Lens: Global Health Security
Entry Type: System Impact
Additional Context: Data collected by UNAIDS in 2026 from countries around the world show that HIV funding disruptions severely impacted HIV prevention, testing, critical interventions addressing barriers to services, and community-led services that reach the people most affected by HIV. UNAIDS notes that prevention programs traditionally relied heavily on donor assistance, with dependency reaching 83% for prevention programs in sub-Saharan Africa.
Devex Researcher Note: PEPFAR funded-programs accounted for 90% of PrEP initiations globally. The decline in uptake is likely the compound effect of reduced outreach programs, supply chain disruptions, and interruptions to communication with recipients resulting from U.S. disruptions and cuts to PEPFAR programming.
Source: UNAIDS

