Additional Context: This information was collected in a survey administered to the 31 organizations that make up the South African TB Think Tank, and jointly analyzed by the Treatment Action Group and Doctors Without Borders, or MSF for its acronym in French. As of May 2025, as much as 70% of South Africa’s HIV and tuberculosis research projects were funded through the NIH, with other programs funded through the CDC and USAID. The projected impact is a loss of 30% of annual income for South African academic and research institutes, and the layoff of hundreds of staff, with direct implications for trial participants and other people living with HIV and tuberculosis worldwide.

Devex Researcher Note: Reporting from July 2025 shows the NIH reversed some of the funding freezes, creating an alternative funding scheme which would allow 280 research and development projects in South Africa to continue. However, it is unclear whether the policy has restored awards that were terminated, and not just frozen.

Source: MSF